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Assistant professor

Qualification :

Specialization : Microbial Physiology & Biochemistry
EXPERIENCE : Teaching / Research) : > 8 years

Characterization of microbial secondary metabolites called siderophores and various symbiotic/antibiotic interactions mediated by them. This includes antifungal and anticancer properties of siderophore, physiological effects on plants along with siderophore mediated heavy metal bioremediation.

  • Publications:
    1. A Khan, P Singh, R Kumar, S Das, RK Singh, U Mina, GK Agrawal, R Rakwal, A Sarkar, A Srivastava*. (2021). Antifungal Activity of Siderophore Isolated From Escherichia coli Against Aspergillus nidulans via Iron-Mediated Oxidative Stress. Frontiers in Microbiology 12, 729032.
    2. A Khan, P Singh, A Chaudhary, R Haque, P Singh, AK Mishra, A Sarkar, A Srivastava*. (2021). Induction of Iron Stress in Hepatocellular Carcinoma Cell Lines by Siderophore of Aspergillus nidulans Towards Promising Anticancer Effect. Biological Trace Element Research (In Press).
    3. P Singh, A Khan, A Priya, R Kant, A Sarkar, M Roy, A Srivastava*. (2021) Induced adaptation as a means of sustained mercury tolerance in Bacillus subtilis. Proceedings of the National Academy of Sciences, India Section B: Biological Sciences 91, 727–735.
    4. P Singh, A Khan, R Kumar, R Kumar, VK Singh, A Srivastava*. (2020) Recent developments in siderotyping: procedure and application. World Journal of Microbiology and Biotechnology 36, 178.
    5. A Khan, P Singh, A Srivastava*. (2020) Iron: Key player in cancer and cell cycle?. Journal of Trace Elements in Medicine and Biology 62, 126582.
    6. A Nath, A Srivastava, N Mithilesh, A Khan, GB Chand, P Singh. (2020) Development of bacterial consortium tolerant to arsenic and endosulfan by isolating bacteria from arsenic contaminated water bodies in Bihar, India. World Journal of Pharmaceutical Research 9(14), 694-714.
    7. A Khan, A Gupta, P Singh, AK Mishra, RK Ranjan, A Srivastava*. (2019) Siderophore assisted cadmium hyper accumulation in Bacillus subtilis. International Microbiology 23: 277– 286.
    8. S Kumari, A Khan, P Singh, SK Dwivedi, KK Ojha, A Srivastava*. (2019) Mitigation of As toxicity in wheat by exogenous application of hydroxamate siderophore of Aspergillus origin. Acta Physiologiae Plantarum, 41, 107.
    9. A Nath, N Mithilesh, S Sinha, P Kashyap, A Srivastava, P Sinha, M Sardana, J K Singh. (2019) Depolarization of plasma membrane components due to Arsenic exposure during spermiogenesis. IOSR Journal of Environmental Science, Toxicology and Food Technology.
    10. GK Satyapal, SK Mishra, A Srivastava, RK Ranjan, K Prakash, R Haque, N Kumar. (2018) Possible bioremediation of arsenic toxicity by isolating indigenous bacteria from the middle Gangetic plain of Bihar, India. Biotechnology Reports, 17, 117–125.
    11. P K Aditya, P Singh, A Srivastava*. (2018) Isolation and characterization of amylase producing thermophilic bacteria from Sita kund in Munger district of Bihar. International Journal of Scientific Research Letters. 1(2), 1 – 9.
    12. A Khan, P Singh, A Srivastava*. (2018) Synthesis, nature and utility of universal iron chelator – Siderophore: A review. Microbiological Research 212-213, 103-111.
    13. A Srivastava, A Singh, SS Singh and AK Mishra. (2017) Salt stress–induced changes in antioxidative defense system and proteome profiles of salt-tolerant and sensitive Frankia strains. Journal of Environmental Science And Health, Part A 52(5), 420 – 428.
    14. M Srivastava, MS Kaushik, A Srivastava, A Singh, E Verma, AK Mishra. (2016) Deciphering the evolutionary affiliations among bacterial strains (Pseudomonas and Frankia sp.) inhabiting same ecological niche using virtual RFLP and simulation-based approaches. 3 Biotech 6, 178.
    15. AK Mishra, PK Singh, P Singh, A Singh, SS Singh, A Srivastava, AK Srivastava, HK Sarma. (2015) Phylogeny and evolutionary genetics of Frankia strains based on 16S rRNA and nifD–K gene sequences. Journal of Basic Microbiology 55(8), 1013–1020.
    16. A Srivastava, AK Mishra. (2014) Regulation of nitrogen metabolism in salt tolerant and salt sensitive Frankia strains. Indian Journal of Experimental Biology 52, 352-358.
    17. A Srivastava, SS Singh and AK Mishra. (2014) Modulation in fatty acid composition influences salinity stress tolerance in Frankia strains. Annals of Microbiology 64, 1315-1323.
    18. A Srivastava, SS Singh, AK Mishra. (2013) Sodium transport and mechanisms of sodium tolerance in Frankia. Journal of Basic Microbiology 53, 163-174.
    19. P Singh, SS Singh, A Srivastava, A Singh, AK Mishra. (2012) Structural, functional and molecular basis of cyanophage-cyanobacterial interactions and its significance. African Journal of Biotechnology 11, 2591-2608.
    20. SS Singh, A Singh, A Srivastava, P Singh, A Singh, AK Mishra. (2010) Characterization of Frankia strains based on physiological, SDS-PAGE of whole cell proteins and RAPD-PCR analyses. World Journal of Microbiology and Biotechnology 26, 985-992.
  • Patent:
  • Book:
    1. Human Implications of Biotechnology (2018) Haque R, Srivastava A, Kumar N. (eds). Shree Publishers & Distributors, New Delhi, India.
  • Book Chapters:
    1. P Singh, A Khan, Anand M, Kumar H, Kumar S, A Srivastava* (2021) Eco-Friendly Applications of Natural Secondary Metabolites and Status of Siderophores. In: Kumar N (ed), Biofuel from microbes and plants: green energy alternative (1st ed), CRC press Taylor and Francis.doi:10.1201/9780429262975-8
    2. P Singh, A Khan, A Srivastava*. Biological Means of Arsenic Minimization with Special Reference to Siderophore (2021) In: Arsenic Toxicity: Challenges and Solutions (ed.) Nitish Kumar. Springer Singapore, pp. 253-278. DOI: 10.1007/978-981-33-6068-6_1. ISBN 978-981-33-6068-6
    3. A Khan, P Singh, A Srivastava*. Microbial Biofuels: An Economic and Eco-Friendly Approach (2020) In: Biotechnology for Biofuels: A Sustainable Green Energy Solution (ed.) Nitish Kumar. Springer, Singapore. Pp- 165-196. DOI- 10.1007/978-981-15-3761-5_7. ISBN 978-981-15-3761-5
    4. P Singh, A Khan, A Srivastava*. Heterocyst and akinete differentiation in cyanobacteria: a view toward cyanobacterial symbiosis (2020) In: Advances in Cyanobacterial Biology (eds.) Prashant Singh, Ajay Kumar, Vipin Kumar Singh, Alok Shrivistava. Academic Press, Elsevier. pp-235-248. DOI- 10.1016/B978-0-12-819311-2.00016-4. ISBN: 978-0-12-819311-2.
    5. S Dey, P Singh and A Srivastava*. Inherent Variability of Closely Related Genera - Anabaena and Nostoc isolated from paddy fields of Patna, Bihar (2018) In: Defining Modern Biology: Plants and Microbes (eds) A Sarkar, V Mandal, S K Sil, S Majumdar, C Barman. ISBN: 978-93-86564-02-3.
    6. A Singh, A Khan and A Srivastava*. Behavior of Anabaena under iron stress condition with reference to siderophore production (2018) In: Human Implications of Biotechnology. (eds) Rizwanul Haque, Amrita Srivastava, Nitish Kumar, Shree Publishers & Distributors, Ansari Road, New Delhi. ISBN: 978-81-8329-862-9.
    7. A Srivastava. Deciphering the basis of salt tolerance and agricultural utility of Frankia strains isolated from Hippophae salicifolia D. Don (2017) In: Plants and Microbes in Ever – Changing Environments. (ed) Satyashila Singh. Nova Science Publishers, New York, USA. ISBN: 9781536109283.
    8. P Singh, A Srivastava.* Impact of rising carbon dioxide (CO2) on plant health and efficacy: An insight to cell metabolism (2016) In: Sustaining future food security in changing environments (eds) Divya Pandey and Abhijit Sarkar, Nova Science Publishers, Inc., New York, pp. 195 – 209. ISBN: 978-1-53610-301-4.
    9. A Srivastava, G.S. Shekhawat. Biofilms: Formation, Sustenance and Significance (2011) In: Recent Advances in Environmental Biotechnology (eds) P.K. Jain, V.K. Gupta and V. Bajpai, Lambert Academic Press, Germany, pp. 24-46. ISBN: 97838443068 73.
    10. A Srivastava, P Singh, A Singh, SS Singh, AK Mishra. Cyanobacteria: Phenotypic to the Genotypic Diversity (2011) In: Microbial Biotechnology & Ecology (eds) D. Vyas, G.S. Paliwal, P.K. Khare, R.K. Gupta, Daya Publications, New Delhi, pp. 41-59. ISBN: 9788170356943
    11. A Srivastava, A Singh, SS Singh, AK Mishra. Frankia-Actinorhizal Symbiosis: An Overview (2009) In: Soil Microflora (eds) R. Gupta, M. Kumar and D. Vyas, Daya Publishing House, New Delhi, pp. 86-101. ISBN 81-7035-597-4
    12. AK Mishra, P Singh, A Singh, A Srivastava, SS Singh. Role of Frankia in Agroforestry (2009) In: Proceedings of the National Seminar on “Agroforestry for Socioeconomic Development of North Eastern Region” held on 11-12th December, 2009, NERIST, Nirjuli, Arunachal Pradesh.
    13. AK Mishra, P Singh, SS Singh, E Shukla, A Srivastava, A Singh. Role of Blue Green Algae in Rural Development (2010) In: Proceedings of the National Seminar on “Transformation in Rural Economy of North East Hills Region in India: Status, Determinant and Prospects” held on 7-8th May, 2010, National Institute of Rural Development, North Eastern Regional Centre, Khanapara, Guwahati, Assam.
  • Awards :
    1. Gold medalist in M.Sc. Bio-Science, Banasthali Vidyapith, Rajasthan
    2. Qualified GATE 2007 with 94.94 percentile
    3. Qualified CSIR JRF in 2007
    4. CSIR-JRF (01.07.2008 to 30.06.2010)
    5. CSIR-SRF (01.07.2010)
    6. Best paper presentation award at “International Conference on Mycology and Plant Pathology Biotechnological Approaches” held on February 27-29, 2012 at Centre of Advances Study in Botany, Banaras Hindu University, Varanasi.
    7. Best oral presentation at “National Symposium on Plant Biology and its Role in Sustainable Food and Energy Production” held on March 17-18, 2012 at Department of Botany, GGV, Bilaspur.
    8. DST Young Scientist Travel Grant – 2012