About Department
Vision and Mission
Academic Program
Faculty
Facilities
Student
Research
eResource
Contact

 

Bioinformatics is a rapidly growing interdisciplinary field of study, involving multiple disciplines of biology, chemistry, physics, mathematics, statistics, pharmaceutical & computer sciences, and information technology. It has wide-ranging applications from marker development and diagnostics to drug discovery and toxicological predictions. To mention few, modeling, simulation and AI techniques, drug lead predictions and optimization, are the most sought-after skills for job-seekers in pharmaceutical and biomedical industries.

With a purpose to open a new department in this frontier area, the foundation of the department was laid in 2011 and for a while it continued as an independent Bioinformatics Programme within the-then Centre for Biological Sciences. In 2018, it acquired full-fledged department status. It is the only department in the entire state of Bihar, and one of the few places of higher learning in Eastern India to promote teaching and research in Bioinformatics & computational sciences.

The department offers two programs: (i) MSc in Bioinformatics, and (ii) PhD in Bioinformatics. In these programmes, the students are trained for various scientific methods and tools, enabling them to better suit for different research laboratories and industries, which require manpower skilled in programming languages, data analytics, machine learning techniques, computational modeling and drug design. Students are provided support and encouragement to gain experience in the department, as well as in established labs in the country, for their project work and to publish their research.

Department Overview

Established in

2011 
(Initially named as Centre for Biological Sciences (Bioinformatics) and since 2018 name changed to Department of Bioinformatics

Employee Strength

Faculty- 07
Staffs - 02

Student Strength

Research Scholar & JRF-19
PG-Students -58
MPhil/PhD Graduated - 02

Placement 2021
(Job, Higher Studies) 

10 (tentative)

Publications & Patent
(Last 5-Years)

Publications- 101
Patent -01
Books - 04

 

 

Board of Studies (BoS)

BoS is a statutory body for each department/centre, primarily responsible for syllabus design and regular update. As described in the Ordinance section 25.10,

The functions of the Board of Studies shall be:-

  • To recommend to the School Board, courses of studies offered by the Department/Centre and continue updating syllabus;
  • To take all steps in accordance with the provisions of the Regulations about teaching and evaluation of various courses/programmes of the Department/Centre;
  • To recommend to the School Board measures for the improvement of teaching and research in the Department/Centre;
  • To constitute panels of experts to be considered for appointment as Examiners, Board of Examiners for various courses/academic programmes and M.Phil./Ph.D. thesis representing various specializations of Departments/Centres; and
  • To perform such other functions as may be assigned to it by the School Board, the Academic Council, the Executive Council and the Vice-Chancellor.

Department Committee (DC)

As enshrined in the Ordinace-26, the Department/Centre Committee (DC/CC) shall consist of the Head of the Department/Centre, as Chairperson ex-officio, and all faculty members of the Department/Centre.

26.2 The Department/Centre Committee shall have the following functions, namely–

  • To make proposals to the Board of Studies on academic programmes concerning teaching and research, and the creation, specialization and abolition of teaching posts;
  • To propose schemes for the maintenance and improvement of the standards of various programmes of study and research of the Department/Centre;
  • To apportion the teaching and co-curricular work of the Department/Centre among the teachers thereof and monitor the proper execution thereof;
  • To consider and decide on the assignment and utilisation of the space, equipment and other assets of the Department/Centre and other matters of general and academic interest of the Department/Centre;
  • To consider and recommend perspectives and major thrust areas for research and to propose research projects to be taken up by the members of the Department/Centre, individually/collectively;
  • To review and apprise the SRC/URC with the current status of research in Department/Centre;
  • To suggest to SRC/URC norms related to qualifications and research experience of a faculty to be recognized as a research degree supervisor and to constitute Department/Centre Research Degree Committee (DRC/CRC);
  • To suggest to University Admission, Teaching and Evaluation Committee (UATEC) on any issue related to admission, teaching, continuous evaluation in courses and students’ assessment of courses, offered by the Department/Centre to improve quality of education.
  • To constitute such Committee(s) comprising members of the Department/Centre, and if necessary external experts, for framing and implementation of rules and regulations related to admission, teaching, continuous evaluation, maintenance of students’ records including alumni affairs as well as promotion of research and development; and
  • To perform such other functions as may be assigned by the Ordinances or Regulations, or by the Vice- Chancellor/Dean/School Board from time to time.

Department Research Degree Committee (DRDC)

Departmental/Centre Research Degree Committee (DRDC/CRDC) deal with all matters connected with the Ph.D. Programme of the Department and report the matter to the University Research Degree Committee (URDC), as per University Ordinance-33. It consists of the Head of Department/Centre as Chairman and other faculties in the department.

Functions of DRDC/CRDC are as follows:

  • Allotment of Supervisor, Co-Supervisor, recording reasons for not admitting a candidate.
  • Recommendation for extension of time for submission of thesis
  • Recommendation to peruse a part of research outside the University
  • Approval of the Course Work
  • Assessment and Grading in Course Work
  • Monitoring the research progress of the candidate
  • Approval of Research plan proposal/language
  • Sanction of duty leave to the Ph.D. candidate
  • Assessment of Ph.D. work through pre-submission seminar
  • Maintaining the record of research paper publications of the candidate
  • 11 Recommendation of panel of experts for thesis evaluation
  • Assessment of revised thesis for satisfactory compliance, if any
  • Arrangement of Viva-voce in the absence of the supervisor
  • Recommendation to waive the Viva-voce

Research Advisory Committee (RAC)

A Research Advisory Committee (RAC) is constituted for every research scholar admitted in PhD programme. The Committee would guide the research scholar to develop the study design and methodology of research and to To periodically review and assist in the progress of the research work of the research scholar. The committee shall have also have power to recommend the co-supervisor and cancellation of registration

Vision

  • To nurture young talent for global competitiveness in providing computational biology solutions and create a hub for research in bioinformatics

Mission

  • To inculcate self motivation and competence in graduates
  • Imparting skills to solve biological problems using computational biology
  • Encourage biologist to adopt computational approaches in research
  • Provide assistance for the critical diseases
  • Upliftment of society in general and local community in particular
  • Objectives of the Program:
  • The core objective of the programme is to provide quality education to the graduates, who want to pursue their career in the emerging areas of Bioinformatics and Computational Biology.
    • To serve as a nodal point for Bioinformatics and its applications
    • To provide industry interface to the students for research project
    • To build skilled manpower for drug design and pharmaceutical industry
  • Program Outcomes:
  • At the end of training, students should:
    • have a understanding of scientific methods, techniques and tools and their applications in Bioinformatics and computational sciences
    • be skilled in data generation, analysis and management and be able to apply the knowledge for scientific enquiry
    • have gained oral presentation and scientific writing skills.
  • Eligibility:
  • Bachelor's degree in Biological Sciences / Agricultural Science / Pharmaceutical Science/Veterinary Science/Medical Science / Mathematics/ Physics/Chemistry /Computer Science/Information Technology or Integrated B.Sc. B.Ed. with 55% marks for General/OBC candidates and 50% marks for SC/ST candidates from any recognised University.
  • Intake: 45
  • Objectives of the Program:
    • To prepare outstanding & skilled computational scientist and professionals, who could effectively translate their skills in bio, pharma and healthcare sectors, and serve in academia to provide quality training and research.
  • Program Outcomes:
  • At the end of training, students should:
    • have a comprehensive understanding of scientific methods and techniques, and their application in Bioinformatics and computational sciences;
    • be able to demonstrate originality in their approach in dealing with scientific problems in computational areas;
    • be skilled in knowledge creation, management and application, and in the planning and implementation of research
    • should be able to critically examine research findings and methodologies
    • have gained oral presentation and scientific writing skills.
  • Eligibility:
  • Master's Degree from any recognised University in Biological Sciences/Agricultural Science/Pharmaceutical Science/Veterinary Science/Medical Science/Physical Science/Chemical Science/Computer Science/IT with 55% in aggregate or its equivalent Grade B in UGC 7 point scale. A Relaxation of 5% of marks from 55 to 50% or equivalent relaxation of Grade for SC/ST/OBC (Non creamy layer)/Differently abled candidates. Candidates having Master Degree in any of the above discipline with specialisation in Bioinformatics or having Master's Degree in Bio-Informatics will be given preference.
  • Intake: Subject to availability of seats as notified
    • Lab facility

Extensive infrastructure facilities have been developed for rigorous training and to carry out research activities. The computer labs have are equipped with latest computers of high configuration having intel i7 multi-core processors. All computers are connected with high band-width internet connection powered by 1 GBPS National Knowledge Network (NKN) of Government of India. These labs have several HP, Dell, Fujitsu & Tyrone workstations and servers for high performance computing.

    • List of instruments& Softwares in the Lab
      • Multiple HP and Dell workstations and servers
      • 26-intel i7 desktop computers
      • 1-RAC Server
      • Accelrys, AMBER & various open source/commercial softwares
    • Lab staffs and their contact
      • Priyatam Manohar Mrinal – Laboratory Attendant
        Qualification: B.Sc.( Zoology)
        Email: priyatammrinal@cub.ac.in
        Contact: 0631-2229-
      • Atul Kumar Tripathi – Laboratory Attendant
        Qualification: M.Sc.
        Email: atulkumar@cub.ac.in
        Contact: 0631-2229-
    •  
S.No. Year Session Enrollment no Name CGPA
1 2021 2019-21 CUSB1903312016 Nikita Krishna 8.67
2 2020 2018-20 CUSB1803312018 Sanjay Kumar Mohanty 9.54
3 2019 2017-19 CUSB1703122009 Kriti Kumari 8.00
4 2018 2016-18 CUSB1603122008 Prasun Kumar Dev 8.19
5 2017 2015-17 CUSB1403122008 Priyanka Rani 8.17
6 2016 2014-16 CUSB1403122021 Shweta Kumari 9.00
7 2015 2013-15 CUSB13312016
8 2014 2012-14 CUSB1203312016
S.No. Research Scholar/JRF/Project staff Photograph Guide Academic Qualification Research Area Achievement/Award /Publication
1 Rakesh Kumar
rakeshbis@cub.ac.in
CUSB1503175001
Contact:7870783312
Dr. Vijay Kr. Singh M.Phil. in Bioinformatics Functional Genomics & microarray/NGS data analysis
Molecular Modelling, Drug Discovery & Molecular Dynamic Simulation
Publications including conference Publications :
  • Kumar, R., Ojha, K. K., Kushwaha, P., & Singh, V. K. (2020). Muscle biopsies differ in relation to expression of fiber-type specific genes. Journal of Diabetology, 11(3), 198.
  • Pratika Singh. Azmi Khan. Rakesh Kumar. Ravinsh Kumar. Vijay Kumar Singh. Amrita Srivastava. (2020). Recent developments in siderotyping: procedure and application. World Journal of Microbiology and Biotechnology. 36:178.
  • Prasanna, P., Kumar, R., Singh, V. K., & Upadhyay, A. (2021). Cloning, purification, and homology modeling of Histone deacetylase in Leishmania donovani. Infection, Genetics and Evolution, 104738.
  • Rakesh Kumar and Vijay Kumar Singh. Investigation of type 2 diabetic responsive genes based on a set of highly co-expressed genes: National Workshop on Big Data and Artificial Intelligence in Biotechnology and Healthcare. (2019).
  • Rakesh Kumar, Krishna Kumar Ojha and Vijay Kumar. Investigation of molecular interaction between A-beta and insulin receptors: An In-silico study. 23rd international conference of the international academy of physical sciences (coniaps xxiii) on advances in physical sciences to achieve sustainable development goals.(2018)
  • Rakesh Kumar and Vijay Kumar Singh. Identification of Hidden Patterns in Gene Expression Data, Given Gene set a Priori: An Application to Diabetes GEPs. VIII International Symposium on Statistics and Optimization in conjunction with XXXVI-Annual Convention of Indian Society for Probability & Statistics (ISPS) and Seminar on Statistical Inference, Sampling and Optimization Techniques & Related Areas. (2016)
  • Rakesh Kumar and Anil Kumar. In silico interaction studies of Resveratrol derivatives with human tyrosinase.1st International Conference on Human Implications of Biotechnology. (2016)
2 Sonu Kumar
CUSB1503175002
sonukumar@cub.ac.in
Contact: +919835431433
Dr. Asheesh Shanker M.Phil. in Bioinformatics Bioinformatics & Genomics Publications
  • Sonu Kumar and Asheesh Shanker (2018) Common, unique, and polymorphic simple sequence repeats in chloroplast genomes of genus Arabidopsis. Vegetos- An International Journal of Plant Science. 31(Special): 125-131.
  • Sonu Kumar and Asheesh Shanker (2018) Bioinformatics resources for the stress biology of plants. In Biotic and Abiotic Stress Tolerance in Plants. Springer, Singapore. (pp. 367-386).
  • Sonu Kumar and Asheesh Shanker (2018) Biological databases for medicinal plant research. In Biotechnological Approaches for Medicinal and Aromatic Plants. Springer, Singapore. (pp. 655-665).
  • Khushbu Anand, Sonu Kumar, Afroz Alam, and Asheesh Shankar (2019) Mining of microsatellites in mitochondrial genomes of order Hypnales (Bryopsida). Plant Science Today. 6 (sp1): 635-638.
  • Sonu Kumar and Asheesh Shanker (2020) Analysis of microsatellites in the mitochondrial genome of Aneura pinguis (L.) Dumort. In Contemporary Research on Bryophytes. Bentham Science Publishers Pte. Ltd. Singapore. (pp. 20-37).
  • Sonu Kumar and Asheesh Shanker (2020) Computational resources for bryology. In Contemporary Research on Bryophytes. Bentham Science Publishers Pte. Ltd. Singapore. (pp. 20-37).
  • Sonu Kumar and Asheesh Shanker (2020) In silico comparative analysis of simple sequence repeats in chloroplast genomes of genus Nymphaea. Journal of Scientific Research. 64(1): 186-192.
  • Sonu Kumar and Asheesh Shanker (2020) Length variation of chloroplast simple sequence repeats in the genus Eucalyptus L'Hér. Plant Science Today. 7(3): 353-359.
  • Sonu Kumar, Kriti Kumari, Anamika Singh, Keshav Kumar, Ashutosh Singh, and Asheesh Shanker (2020) Development and analysis of simple sequence repeats in chloroplast genomes of genus Saccharum: a computational study. In Recent Trends in ‘Computational Omics’. Nova Science Publishers, Inc.
  • Sonu Kumar, Swati Kumari, and Asheesh Shanker (2020) In Silico Mining of Simple Sequence Repeats in Mitochondrial Genomes of Genus Orthotrichum. Journal of Scientific Research. 64(2): 179-182.
3 Agnik Haldar
halderagnik@gmail.com
agnikhaldar@cusb.ac.in
CUSB1803375001
Dr. Ajay Kumar Singh M.Tech. Bioinformatics Functional Genomics, Transcriptomics, Statistical NGS Data Analysis, Cancer informatics Publications
  • Haldar A, Mitra S, Chakrabarti J. Perspective on long noncoding RNA functionality. Transl Cancer Res 2017;6 S1049-S1053. doi: 10.21037/tcr.2017.07.20
  • Sayak Ganguli, Mitra Sanga, Halder Agnik, Gupta Sohini, Chakrabarti Jayprokas. (2017). Databases: a comprehensive resource of noncoding RNAs. Cancer and Non Coding RNAs.
  • Mitra Sanga, Halder Agnik, Gupta Sohini, Sayak Ganguli, Chakrabarti Jayprokas. (2018). A Comparative Evaluation of Emerging Databases and Tools for Cancer Noncoding RNAs. Cancer and Non Coding RNAs. Academic Press. 10.1016/B978-0-12-811022-5.00027-9.
  • Haldar A., Mandal R. (2018) A transcriptomic approach towards understanding virulence regulation of Salmonella serovars Typhi, Typhimurium and Paratyphi A.
  • Haldar A., Yadav K., Katara P.C., Singh A.K.*. (2020) Bioinformatics resources for the prediction of cancer prognosis and its recurrence. Recent trends in computational omics, concepts and Methodology. Nova Science Publishers, U.S.A
  • Haldar A., Singh A.K.*. (2020) Next-generation sequence analysis for clinical applications. Translational Bioinformatics Applications in Healthcare. CRC Publication.
  • Conferences
  • Haldar A., Singh A.K.* A transcriptomic analysis on long non coding RNA role in oral cancer inhibition. National Conference on Biological, Biochemical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021), conducted by Department of Biotechnology National Institute of Technology Warangal, Telangana, India
  • Awards
  • University Gold Medal in Masters of Engineering, 2018 (for highest academic standing at postgraduate level)
  • Best Oral Presentation Award
    Haldar A., Singh A.K.* A transcriptomic analysis on long non coding RNA role in oral cancer inhibition. National Conference on Biological, Biochemical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021), conducted by Department of Biotechnology National Institute of Technology Warangal, Telangana, India
4 Bikash Kumar rajak
bikash@cusb.ac.in
bkrbikash0@gmail.com
CUSB1803375001
Dr. Durg Vijay Singh B.Sc. Botany Hons.
M.Sc. Bioinformatics
Molecular Dynamics Simulation and Computer-aided Drug Discovery Publication/conference
  • Rajak, B.K, Rani. P., Mandal.P. and Singh, D.V 2021, January. “Identification of lead molecule against Acetyl-CoA Carboxylases of Phalaris minor” National Conference on Biological, Biochemical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021), conducted by Department of Biotechnology National Institute of Technology Warangal, Telangana, India (Got Best Oral Presentation Award)
  • Rani.P, Rajak, B.K 2021, Mandal,P. Singh D.V January. “Discovery of Lead Herbicide Molecules Against ACCase Protein of Phalaris Minor” National-e Conference on Bioremediation and Detoxification of Environmental Pollutants” organised by Department of Zoology Lalit Narayan Mithila University Darbhanga, Bihar India
5 Keerti Kumar yadav
keerti@cusb.ac.in
7836071067
Dr. Ajay Kumar Singh M.Tech Bioinformatics Systems Biology,Cancer informatics, CADD
  • Sikka P, Nath A, & Yadav KK. (2016). Insilico characterization of novel PH20 hyaluronidase protein sequences of murrah (Bubalus bubalis) bulls. Applied Biological Research, 18(2), 171-177
  • Haldar A, Yadav KK, Katara P, Singh AK, (2020). “Bioinformatics resource for prediction of cancer prognosis and it’s recurrence, Recent trends in computational omics concepts and methodologies “, NOVA Science Publication
  • Yadav KK, Singh AK, ”Oral cancer identification candidate genes by integrated Protein-Protein interaction and Systems biology approach” Two Day Online National Conference on Biological, Biochemical, Biomedical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021) held on 29-30 January 2021
6 Kiran Kr A
kirankumar@cusb.ac.in
Prof. R.S Rathore M.Sc.Biochemistry Molecular Modeling & Drug Design GATE Qualified.
Publications including conference Publications:
  • Kiran Kr A
    kirankumar@cusb.ac.in
  • Angamba Meetei Potshangbam, Potshangbam Nongdam, A. Kiran Kumar and R.S. Rathore*, “Phenylbenzopyrone of flavonoids as a potential scaffold to prevent SARS-CoV-2 replication by inhibiting its MPRO main protease”, Current Pharmaceutical Biotechnology (2021)22:1.
  • Kiran kumar. A, R.S Rathore, R.S Upadhyayula. Characteristic differences at the interfacial hotspot regions of the protein-protein and protein-peptide complexes (2021).
  • Ganga Bhavani. D., Muni Kumari. A* and Kiran Kumar. A (2015). Chikckpea Endophytic Bacteria Inhibiting Dry Root Rot Fungus Rhizoctonia bataticola. International Journal of Scientific and Engineering Research. 6(2): 83-85.ISSN:2229-5518.
  • Kiran Kumar.A, Characterization of Protein-Protein and Protein-Peptide Interactions: Implication for Biologics Design (February 2, 2020). Proceedings of International Conference on Drug Discovery (ICDD) 2020.
  • Kiran Kumar. A, Machine learning Prediction of Transient and Permanent Protein Interactions using Weka (January 29-30, 2021). Proceedings of Two-Day Online National Conference on Biological, Biochemical,Biomedical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021)
  • A. Kiran Kumar and Dr. A. Muni Kumari.Effect of Lipoxygenase enzyme to downy mildew disease in Foxtail Millet’ Proceedings of International Conference on Advances in Plant and Microbe Research (ICAPMR 2016)Acharya Nagarjuna University, Guntur, A. P
  • A. Kiran Kumar and Dr. A. Muni Kumari. ―’Lox in Resistance of foxtail millet to Blast Infection’ Proceedings of UGC Sponsored National Seminar on Emerging Trends in Genetics and Genomics Research 13-14 February 2014. Dept of Genetics and Genomics Yogi Vemana University, Kadapa, A.P.
7 Praffulla Kumar Arya
CUSB1803375005
praffullaarya@cusb.ac.in
Mobile: 7979031632
Dr. Anil Kumar M.Sc. Bioinformatics Biological Database Development Chapter Publications
  • Kumar, A., & Arya, P, (2020). Database Resources for Cyanobacterial Research. In P. K. Singh & A. K. Shrivastava (Authors), Advances in cyanobacterial biology (1st ed., pp. 47-54). London, United Kingdom: Academic Press.
  • Kumar, A., & Arya, P, (2020). Database Resource for Drug Discovery. In D.B. Singh (Authors), Computer-aided drug design. Springer Nature, Singapore.
8 Kriti Kumari
kriti@cusb.ac.in
Dr. Asheesh Shanker M.Sc Bioinformatics Evolutionary biology and computer-aided drug discovery
  • Sonu Kumar, Kriti Kumari, Anamika Singh, Keshav Kumar, Ashutosh Singh, and Asheesh Shanker (2020) Development and analysis of simple sequence repeats in chloroplast genomes of genus Saccharum: a computational study. In Recent Trends in ‘Computational Omics’. Nova Science Publishers, Inc.
9 Pranabesh Mandal
pranabesh@cusb.ac.in
Mobile: 7908836982
Dr. Durg Vijay Singh M.Sc. Bioinformatics Molecular Dynamics Simulation and Computer-aided Drug Discovery Awards received:

-Best Poster Presentation Award-
  • Rani, P., Mandal, P., & Singh, D.V., 2019, November. Efficacy of rationally synthesised herbicides in Phalaris minor susceptible and resistant weeds of wheat crop. 1 st National Agrochemicals Congress: County’s Status on Various Fronts of Agrochemicals, ICAR-Indian Agricultural Research Institute-New Delhi.
10 Priyanka rani
priyanka.rani.453@gmail.com
priyanka@cusb.ac.in
Dr. Durg Vijay Singh B.Sc. Industrial microbiology (2015)
M.Sc. Bioinformatics (2017)
Structural biology, Molecular modelling, Molecular docking, Dynamics study,
Computer Aided-Drug discovery Microbiology
Published research articles:
  • Rani, P., Kumari, P., & Swayamprabha, S. (2015). Comparison between chemical and natural disinfectant against Escherichia coli and Streptococcus pyogenes. IRIS, V: 45-51.
  • Bera, K., Rani, P., Kishor, G., Agarwal, S., Kumar, A., & Singh, D. V. (2018). Structural elucidation of transmembrane domain zero (TMD0) of EcdL: A multidrug resistance-associated protein (MRP) family of ATP-binding cassette transporter protein revealed by atomistic simulation. Journal of Biomolecular Structure and Dynamics, 36(11), 2938-2950.
  • Rani, P., Kumari, J., Agarwal, S., & Singh, D. V. (2019). Binding mode of aryloxyphenoxypropionate (FOP) and cyclohexanedione (DIM) groups of herbicides at the carboxyl transferase (CT) domai of Acetyl-CoA carboxylase of Phalaris minor. Network Modeling Analysis in Health Informatics and Bioinformatics, 8(1), 1-14.
  • Conferences:
    -Oral Presentation-
  • Rani, P., Nijeta., & Singh, D.V., 2018, November. Strategic development of herbicide to combat the massive problem of Phalaris minor weed, through computational approach. ISWS Golden Jubilee Conference; hald at ICAR-Directorate of Weed Research, Jabalpur. -Poster Presentation-
  • Rani, P., & Chakarborty, S.S., 2018, August. In silico drug design using pharmacophore modeling, virtual screening, and molecular docking to design inhibitors against human Bone Morphogenetic Protein-1 as new lead molecules for therapy. Two days international seminar on Recent trends in science towards sustainable development, Indian Chemical Society, Acharya Prafulla Chandra College, Kolkata.
  • Rani, P., Mandal, P., & Singh, D.V., 2019, November. Efficacy of rationally synthesised herbicides in Phalaris minor susceptible and resistant weeds of wheat crop. 1 st National Agrochemicals Congress: County’s Status on Various Fronts of Agrochemicals, ICAR-Indian Agricultural Research Institute-New Delhi.
  • Rajak, B.K., Rani, P., Mandal, P., & singh, D.V. 2021, January. Identification of lead molecule against Acetyl-CoA Carboxylases Of Phalaris minor. National Conference on Biological, Biochemical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021). Department of Biotechnology, National Institute of Technology Warangal, Telengana-India.
  • Rani, P., Rajak, B.K., Mandal, P., & Singh, D.V., 2021 January. Discovery of lead herbicide molecules against ACCase protein of Phalaris minor. National e-conference: Bioremediation and Detoxification of Environmental Pollutants, Department of Zoology, Lalit Narayan Mithila University, Darbhanga-Bihar.
  • Awards received:
    -Best Poster Presentation Award-
  • Rani, P., Mandal, P., & Singh, D.V., 2019, November. Efficacy of rationally synthesised herbicides in Phalaris minor susceptible and resistant weeds of wheat crop. 1 st National Agrochemicals Congress: County’s Status on Various Fronts of Agrochemicals, ICAR-Indian Agricultural Research Institute-New Delhi.
11 SM Shayez karim Prof. R.S Rathore M.Tech Bioinformatics Brain Connectome Analysis
12 Suchitra Singh
suchitrasingh@cusb.ac.in
CUSB1903375006
Dr.Ajay Kumar Singh M.Sc Bioinformatics Molecular modelling and Drug Design Publications and Conferences
  • Singh, S., & Singh, A. K. (2020). Mutated USP9X-Associated TRIM33 Inhibition in the Metastasis of Gingivobuccal Oral Squamous Cell Carcinoma Eurasian Journal of Medicine and Oncology (EJMO), 4(4):309-318
  • Singh S., Singh A.K., Porphyromonas gingivalis virulence factors Inhibitors screening in oral squamous cell carcinoma (OSCC) Two Day Online National Conference on Biological, Biochemical, Biomedical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021) held on 29-30 January 2021
13 Sumanta kumar Sahu
sumanta@cusb.ac.in
Mob:9937209313
Dr. Krishna Kumar Ojha M.Sc. Bioinformatics Rational Drug Design & QSAR
14 Gyan Prakash Rai
Email: gyanprakash@cusb.ac.in
Mob:8860759395
Dr. Asheesh Shanker M.Sc. Bioinformatics
15 Mayank Kumar
Email mayank2801@gmail.com
Contact 9308953868
Prof. R.S. Rathore Master in Computer Application Protein Structure Prediction UGC - NET (June 2020 ) Qualified
16 Kirshnendu
Krishnendubarik@gmail.com
7008641931
Dr Anil kumar MSc Bioinformatics Biological Database Development
17 Niharika
niharika@cusb.ac.in
8228934884
Dr.Vijay Kumar Singh MSc. Bioinformatics Transcriptomics
18 Piyush
kumarpiyush285@gmail.com
CUSB2003375005
Dr. Ajay Kumar Singh M.tech Bioinformatics Drug Discovery Oral Presentation
  • Piyush K Yadav, Ajay K Singh* ‘Hepcidin as iron chelation target in Beta thalassemia Major : An in-silico approach’ Two Day Online National Conference on Biological, Biochemical, Biomedical, Bioenergy and Environmental Biotechnology (NCB4EBT-2021) held on 29-30 January 2021
  • Piyush K Yadav, Ajay K Singh* ‘Iron overload targets and their effects in Beta-thalassemia major’ Two day International Conference on Frontier Areas of Chemistry held on 28-29 Feb 2020

 

MSc (2021-23) Batch

r. No.

Enrolment_No

NAME OF THE APPLICANT

EMAIL

1

CUSB2103312001

ABHISHEK CHOUDHARY

choudharyabhi3120@gmail.com

2

CUSB2103312002

ABHISHEK KUMAR

abhishekkumar141099@gmail.com

3

CUSB2103312003

AFSA NAAZ

ehsankaisal@gmail.com

4

CUSB2103312004

ANIRUDDHYA MUKHERJEE

aniruddhya08@gmail.com

5

CUSB2103312005

ANKITA SUBHADARSANI PARIDA

ankitasubhadarsaniparida@gmail.com

6

CUSB2103312006

ANMOL SHARMA

anmolsharma7121@gmail.com

7

CUSB2103312007

ANSHUL VERMA

anshulverma2k1@gmail.com

8

CUSB2103312008

FIZZA KHAN

khanfizza27@gmail.com

9

CUSB2103312009

HARSH KUMAR

mohitraj9576@gmail.com

10

CUSB2103312010

HASEEB  AHMAD

haseebahmad789@gmail.com

11

CUSB2103312011

JAGRITI SHUKLA

jagritip.s12@gmail.com

12

CUSB2103312012

JYOTI MURMU

murmujyoti47@gmail.com

13

CUSB2103312013

KOPAL SINGH

kopal.somvanshi@gmail.com

14

CUSB2103312014

KRUTIDEEPA ROUT

krutirout002@gmail.com

15

CUSB2103312015

NEHA KUMARI

nehakr20aug@gmail.com

16

CUSB2103312016

NISHANT RAJ

nisntraj@gmail.com

17

CUSB2103312017

PALLAVI SINGH

words.florence@gmail.com

18

CUSB2103312018

PRABIR BARMAN

barmanprabir02@gmail.com

19

CUSB2103312019

RAVI SHANKAR SHARMA

Mr.ravishankar.sharma@gmail.com

20

CUSB2103312020

REDAM SAHA

redamsaha555@gmail.com

21

CUSB2103312021

RITIKA SINGH

ritikaa198@gmail.com

22

CUSB2103312022

SAFEER KHAN

ksafeer098@gmail.com

23

CUSB2103312023

SAURAV KUMAR

Kumarsaurav787059@gmail.com

24

CUSB2103312024

SHREYA BHARDVAJ

bhardwajshreya175@gmail.com

25

CUSB2103312025

SONALI SINHA

sonalsonali.sinha@gmail.com

26

CUSB2103312026

SREESHMA RAJ K

sreeshmaraj72@gmail.com

27

CUSB2103312027

SUBHASHREE SAHU

sushreeshruti440@gmail.com

28

CUSB2103312028

SUGAM KUMAR PATEL

ptlsugam@gmail.com

29

CUSB2103312029

SUMAIYA KHATUN

sumi15live@gmail.com

30

CUSB2103312030

SUMAN KUMARI

pushpraj.vishwajeet@gmail.com

31

CUSB2103312031

SUSHREE ADARSHEE SAHU

adarsheea@gmail.com

32

CUSB2103312032

SWETA

swetasingh.7jan@gmail.com

33

CUSB2103312033

YUKTI SINGH

singhyukti7@gmail.com

 

 

 

 

 

MSc(2020-22)

 Batch

 

 

Enrolment No.

Name of Student

E-mail of student(personal)

1

CUSB2003312001

ANANYA KASHYAP

kashyapananya46@gmail.com

2

CUSB2003312002

ANNAPURNA KUMARI

annapurnakumari945@gmail.com

3

CUSB2003312003

ANWESHA DHAL SAMANTA

dhalanwesha9@gmail.com

4

CUSB2003312004

ASHISH PRATIM MAHANTA

ashishpratim@gmail.com

5

CUSB2003312005

ATUL ABHISHEK

atulabhishek2010@gmail.com

6

CUSB2003312006

GARIMA KUMARI

kgarima147@gmail.com

7

CUSB2003312007

GAURAV KUMAR

gauravguptasatsa@gmail.com

8

CUSB2003312008

H KIRAN

kiranrekhahari@gmail.com

9

CUSB2003312009

KISHAN KUMAR

kkishan593@gmail.com

10

CUSB2003312010

MADHVI KUMARI SINHA

madhukrsinha31@gmail.com

11

CUSB2003312011

MANAVI KUMARI

manavikumari9@gmail.com

12

CUSB2003312012

MANISHA MOHANTA

munnamohanta71686@gmail.com

13

CUSB2003312013

NISHANT SHEKHAR

nishant.shekhar776@gmail.com

14

CUSB2003312014

POOJA KUMARI

pkri7225@gmail.com

15

CUSB2003312015

PRIYANSU BEHERA

pbpriyansu@gmail.com

16

CUSB2003312017

RAJESH MISHRA

shakhtlaunda1509@gmail.com

17

CUSB2003312018

SHRABANTI ACHARYA

aloke.kumar28@gmail.com

18

CUSB2003312023

TRISHULA MITRA

trishulamitra@gmail.com

       

19

CUSB2003312026

Rashmi Kumari

rashmikri1819@gmail.com

 

  • Project
    1. Dr. Durg Vijay Singh PI, UGC (2013-15; 6 lacs) project entitled Design and development of inhibitors against Nucleotide Binding Domain of P-gp for enhancing Bioavailability and reversal of multidrug resistance
    2. Dr. Durg Vijay Singh, PI, DST Kiran (2014-15; 3.26 lacs) project entitled Design and Development of herbicide against carboxyl-terminal (CT) domain of ACCase of P.minor to regain resistivity in resistance biotypes
    3. Dr. Vijay Kr. Singh PI, SERB (2016-20; 14 Lakh) project entitled Identification of molecular species that have potential to compete with insulin for receptor binding
    4. Dr. Durg Vijay Singh PI DST-SERB (2016-19; 31 lacs) project entitled Design and Development of Herbicide to Regain Sensitivity in Phalaris Minor Resistant Biotypes
    5. Dr. Ajay Kr. Singh, PI Dr. Anil Kumar (Co-PI) ICMR (2019-Ongoing; 35 lacs) project entitled In-Silico study on potent inhibitors against iron overload and cardiac arrhythmia in beta-thalassemia (RP-56).
    6. Dr. Durg Vijay Singh (PI) and Dr. Girish Chandra (Co-PI) ICMR (2020-ongoing; 31 lacs) project entitled Rational approach of antibiotic discovery and development against, a staphylococcus aureus serine-threonine phosphatases (Stp) protein (Project ID RP-60).
    7. Dr. Vijay Kr. Singh Dr. K.K. Ojha (Co-PI) ICMR (2020-Ongoing; 20 lacs) project entitled Gene interaction landscape inferred from expression data to search for diabetes effector molecules (Ref. 2020-3854)
    8. Dr. Durg Vijay Singh (PI), Prof. RS Rathore (Co-PI), Dr. Girish Chandra (Co-PI) (2021 Ongoing 50.37 Lakh) Development of herbicides against Acetyl CoA Carboxylase to address resistance and cross-resistance against Phalaris minor: A weed of wheat crop field.”

     

  • Specific areas of research

    Disease Biology using modeling and omics approaches: The research in the Department of Bioinformatics, is primarily focused towards understanding the underlying process in disorders, with special emphasis on neurodegenerative, respiratory, monogenic & metabolic disorders, infectious disease & cancer.

    1. New algorithms and database have been developed to provide solution for drug and biologics design such as Databases of therapeutic targets and novel leads pertaining to natural products (MedPServer), de novo peptide design (Conflore), curcumin analogs and their molecular & disease targets (CRDB), a workflow for complete 3D-QSAR modeling, virtual screening & design (3D-QServer), simple sequence repeats database, and online server to detect simple sequence repeats with length variation etc.
    2. Analysis of muscle transcriptome to identify biologically relevant class of diabetic patient: We are analyzing large transcriptome datasets to identify subset of diabetic subjects having homogeneous expression of genes related to selected biological processes/pathways.
    3. Genome characterization of gall bladder cancer from Indo-Gangetic belt of India
    4. Evolutionary sequence analysis to detect drug resistance in pathogens
    5. Role of lnc RNA in oral and cervical cancer to understand the mechanism and its significance in oncogenesis.
    6. In silico study on potent inhibitors against iron overload and Cardiac arrhythmia in beta thalassemia
    7. Development (Design, Synthesis and Biological Evaluation) of novel Dual-binding Cation-π Inhibitors of AChE:
    8. Design of flavonoid based SARS-CoV-2 MPRO inhibitors
    9. Identification of Herb-based Lead Molecules, Optimization and Testing using case study of herbs available in Indian sub-continent for Asthma & Respiratory-tract Infection
    10. Other areas:
      Design and development of active molecule against herbicide resistance weeds & validation of leads through wet-lab and field assay as multiple and cross resistances in weeds is a major threat in grain production.
      o Comparative genomics of prokaryotes: To estimate the origin of replication site based on the nucleotide frequency of the prokaryotic genomes.
  • Research Publications

    2022

    1. Haldar, A., Singh, A.K. The association of long non-coding RNA in the prognosis of oral squamous cell carcinoma. Genes Genom (2022). https://doi.org/10.1007/s13258-021-01194-w.

    2021

    1. PA Meetei, P. Nongdam, A Kiran Kumar, RS Rathore., (2021), Phenylbenzopyrone of flavonoids as a potential scaffold to prevent SARS-CoV-2 replication by inhibiting its M PRO main protease. Current Pharmaceutical Biotechnology. In press.
    2. Mahesha N, Yathirajan HS, Nagma Banu HA, Kalluraya B, Rathore RS and Glidewell CG. Formation of 1-(thia­zol-2-yl)-4,5-di­hydropyrazoles from simple precursors: synthesis, spectroscopic characterization and the structures of an inter­mediate and two products. Acta Crystallographica Section E: Crystallographic Communications (IUCr/Wiley). (2021). E77, 975-981
    3. Prasanna, P., Kumar, R., Singh, V. K., & Upadhyay, A. (2021). Cloning, purification, and homology modeling of Histone deacetylase in Leishmania donovani. Infection, Genetics and Evolution, 104738. (IF - 2.77)
    4. Priya P, Shanker A (2021) Coevolutionary forces shaping the fitness of SARS-CoV-2 spike glycoprotein against human receptor ACE2. Infection, Genetics and Evolution 87: 104646
    5. Nandan Kumar, Priyanka Rani, Shikha Agarwal Durg Vijay Singh "6-Ethoxy-4-N-(2-Morpholin-4-Ylethyl)-2-N-Propan-2- yl-1,3,5-Triazine-2,4-Diamine Endows Herbicidal Activity Against Phalaris Minor a Weed of Wheat Crop Field: An in-Silico and Experimental Approaches of Herbicide Discovery" Journal of molecular modeling 2021 (Accepted)

    2020

    1. An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase, AM Potshangbam, A Nandeibam, T Amom, N Potshangbam, H Rahaman, RS Rathore, Journal of Biomolecular Structure and Dynamics, 1-13 (2020) in press
    2. Fifteen 4-(2-methoxyphenyl) piperazin-1-ium salts containing organic anions: supramolecular assembly in zero, one, two and three dimensions, C Harish Chinthal, CN Kavitha, HS Yathirajan, S, RS Rathore, C.G. Glidewell, Acta Crystallographica Section E: Crystallographic Communications 76 (11) 2020.
    3. K Kumar Reddy, R S Rathore , P Srujana, R R Burri, C Ravikumar Reddy, M Sumakanth, Pallu Reddanna, M Rami Reddy, Mini Rev Med Chem. 2020;20, 1179-1187. Performance Evaluation of Docking Programs- Glide, GOLD, AutoDock & SurflexDock, Using Free Energy Perturbation Reference Data: A Case Study of Fructose-1, 6-bisphosphatase-AMP Analogs. doi: 10.2174/1389557520666200526183353.
    4. Kiran Kumar, H. S. Yathirajan, Asma, N. Manju, B. Kalluraya, R. S. Rathore and C. Glidewell (2020) Acta Crystallographica E (Wiley/IUCr). E76, 683-691. Functionalized 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(4-substituted-phen­yl)prop-2-en-1-ones: synthetic pathway, and the structures of six examples. https://doi.org/10.1107/S2056989020005113
    5. Naresh Damuka, K. Kurumurty, P. Angamba Meetei, R.S. Rathore, A.K. Kondapi and V. Vindal, (2020) Pharmacological Reports (Springer Nature). In press. Discovery of Dual Cation-π Inhibitors of Acetylcholinesterase: Design, Synthesis and Biological Evaluation. https://doi.org/10.1007/s43440-020-00086-2
    6. Angamba Meetei, R.S. Rathore, P. Nongdam, (2020) Heliyon (Cell Press) 6(2), e033782019. Discovery of sulfone-resistant dihydropteroate synthase (DHPS) as a target enzyme for kaempferol, a natural flavonoid. https://doi.org/10.1016/j.heliyon.2020.e03378
    7. A.E. Shaibah, H.S. Yathirajan, N. Manju, B. Kalluraya, R.S. Rathore, C. Glidewell (2020) Acta Crystallographica E (Wiley/IUCr) E76, 48-52. Two isostructural 3-(5-ar­yloxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)-1-(thio­phen-2-yl)prop-2-en-1-ones: disorder and supra­molecular assembly. https://doi.org/10.1107/S205698901901658X
    8. A. E. Shaibah, H. S. Yathirajan, Asma, N. Manju, B. Kalluraya, R. S. Rathore and C. Glidewell, (2020) Acta Crystallographica E (Wiley/IUCr) E76, 360-365. Conversion of di­aryl­chalcones into 4,5-di­hydro­pyrazole-1-carbo­thio­amides: mol­ecular and supra­molecular structures of two precursors and three products. https://doi.org/10.1107/S2056989020001735
    9. Jayaswal PK, Shanker A, Singh NK (2020) Genome wide annotation and characterization of young, intact long terminal repeat retrotransposons (In-LTR-RTs) of seven legume species. Genetica 148: 253-268.
    10. Kumar S, Kumari S, Shanker A (2020) In silico mining of simple sequence repeats in mitochondrial genomes of genus Orthotrichum. Journal of Scientific Research 64: 179-182.
    11. Kumar S, Shanker A (2020) Length variation of chloroplast simple sequence repeats in the genus Eucalyptus L’Hér. Plant Science Today 7(3): 353-359
    12. Jayaswal PK, Shanker A, Singh NK (2020) Genome-wide comparative and evolutionary analysis of transposable elements in eight different legume plants Indian Journal of Agricultural Sciences 90: 1025-1031.
    13. Kumar S, Shanker A (2020) In silico comparative analysis of simple sequence repeats in chloroplast genomes of genus Nymphaea. Journal of Scientific Research 64: 186-192.
    14. Suchitra Singh & AK Singh (2020) Mutated USP9X-Associated TRIM33 Inhibition in the Metastasis of Gingivobuccal Oral Squamous Cell Carcinoma EJMO. 2020; 4(4): 309-318
    15. Kamboj M., Jain K., Singh D.P., Singh A.K. Chaturvedi De., Molecular modeling, in-silico docking and antibacterial studies of novel template wangled macrocyclic complexes involving isatin moiety. Journal of Molecular Structure, Elsevier, 2020 (1207) Volume 1207, 5 May 2020, 127602 (Impact Factor 2.120).
    16. Rani, S., Singh, A.K., Paswan, R.R. et al. Preparation, Characterization and Antibacterial Evaluation of Soy Protein Isolate Biopolymeric Films Loaded with Nalidixic Acid. J Polym Environ (2020). 28, 1841–1850(2020). [Impact Factor 2.896].
    17. Tiwari S.K., Singh A.K., Singh A (2020). In-silico primer designing and PCR for detection of novel coronavirus-19, Journal of Infection and Public Health, (2020) 13(12), 1885-1886. Elsevier. (Impact factor : 2.447)
    18. Chandra G., Patel S., Panchal M., Singh D.V. (2020) S-Adenosyl-L-homocysteine hydrolase: Its Inhibitory Activity against Plasmodium falciparum and Development of Malaria Drugs. Mini Rev Med Chem . doi: 10.2174/1389557521666201218155321. (I.F.-3.0
    19. Singh, P., Khan, A., Kumar, R., Kumar, R., Singh, V. K., & Srivastava, A. (2020). Recent developments in siderotyping: procedure and application. World Journal of Microbiology and Biotechnology, 36(12), 1-15. (IF - 2.44).
    20. Rai, N. K., Mathur, S., Singh, S. K., Tiwari, M., Singh, V. K., Haque, R.,Tiwari, S., & Sharma, L. K. (2020). Differential regulation of mitochondrial complex I and oxidative stress based on metastatic potential of colorectal cancer cells. Oncology letters20(6), 1-1.
    21. Kumar R, Ojha KK, Kushwaha P, Singh VK. Muscle biopsies differ in relation to expression of fiber‐type specific genes. J Diabetol 2020;11:198‐203

    Patent

    1. Title:6-ethoxy-4-n-(2-morpholin-4-ylethyl)-2-n-propan-2-yl-1,3,5-triazine-2,4-diamine endowed with herbicidal activity against susceptible and resistant biotypes of Phalaris minor. Inventor: Durg Vijay Singh et.al., (2020). Field of Invention: Pharmaceuticals

 

E-Resources for Courses

 

Course Code

Course Name

Question papers (Previous Years)

Notes and Presentations

Video and Suggested readings

MSBIS1001C04

Introduction to Bioinformatics

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS1002C04

Cell and Molecular Biology

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS1003C04

Mathematics and Statistics with R

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS1004C04

Linux and Shell Programming

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS1005C04

Programming with C

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2001C04

Algorithms in Bioinformatics

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2002C04

Biomolecular Modelling & Simulations

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2003C04

Programming with Perl

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2004C04

Genetics and Genomics

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2005C04

Evolution and Molecular Phylogeny

2021 

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3001C04

Chemoinformatics and Drug Design

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3002C04

Transcriptomics and Proteomics

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3003C04

DBMS and Web Technology

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3004C04

Minor Project (Review of Literature, Seminar, and Research Problem Definition)

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS1001E04

Biochemistry and Immunology

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS2001E04

Whole exome sequencing data analysis

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3001E04

Big Data Analytics and Health Informatics

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3002E04

Programming with Python

2021

2020

2019

Lecture-1

Lecture-2

 

 

MSBIS3003E04

Systems Biology

2021

2020

2019

Lecture-1

Lecture-2

 

 

 

 

 

 

 

 

Course Assessment Design - MSc

  1. Semester –I

  2. Semester –II

  3. Semester –III

  4. Semester-IV

 

In-house Developed Softwares and Databases

 1. Event Management System

 2. MedPServer: Natural Product based Database and Target Identifications

Gallery

 

Department of Bioinformatics

  • Present Head
HOD Name Period Contact Image
Dr. Asheesh Shanker Aug 28, 2021-Onwards Contact : +91 -9414478655
Email: asheesh@cusb.ac.in
  • Former Heads
  1. Prof. R.S. Rathore (Jul 20, 2018 to Aug 27, 2021)
Office Staff Email Id Contact Image
Manish Raj, Upper Division Clerk manishraj@cub.ac.in +91-74882 25815