Dr. Ajay Kumar Singh

Dr. Ajay Kumar Singh working as Associate Professor in department of Bioinformatics of Central University of South Bihar, Gaya. He has earned his doctorate in Bioinformatics from Dr. APJ Abdul Kalam Technical University, Lucknow (formerly as UPTU, Lucknow), M.Tech.-IT (Specialization in Bioinformatics from I.I.I.T, Allahabad and M.Sc. Biotechnology from C.S.J.M. University, Kanpur. He started his research carrier during his Ph.D on topic “Design and development of antitumor and anti-angiogenic drugs specially enzyme inhibitors for oral and cervical cancers”. He and his team (Ph.D Scholars/JRF) working on following topics:

• An Epigenetic and transcriptomic study on lncRNA role in oral and cervical cancer Inhibition (Mr. Agnik Haldar, Ph.D student).
• Identification of inhibitors against oral cancer targets through systems biology approach. (Mr. Keerti Kumar Yadav, Ph.D student)
• Insilico Inhibitors screening against virulence factors of Porphyromonas gingivalis in oral squamous cell carcinoma (OSCC) Ph.D student)
• Insilico study on potent inhibitors against iron overload and Cardiac arrhythmia in beta thalassemia (Mr. Piyush Kumar Yadav, Phd student & JRF Under ICMR funded Project)

2009

1. Singh A.K., Misra K*., Paper titled “In silico study of interactions of curcumin and it’s naturally occurring analogs with Human papilloma virus 16 E6 protein: designing of a herbal drug for oral and cervical cancer accepted for Oral and Poster Presentation in” 1st International Conference in Bioinformatics and Computational Biology (BICoB 2009) held in holiday Inn Downtown- Superdome, New Orleans, Louisiana, USA, from April 8-10, 2009.

2011

1. Singh A.K.a, Misra Kb., Rath S.K.b “Identification of epitopes in Indian human papilloma virus 16 E6: a bioinformatics approach”. J. Virol. Methods. 2011, 177(1):26-30 (Impact factor: 2.623). DOI: 10.1016/j.jviromet.2011.06.006.

2012

1. Singh A.K., Misra K*., “In silico approach for designing potent inhibitors against polymerase PB2 (Influenza A virus: H1N1)”,  Proc. Natl. Acad. Sci., India, Sect. B Biol. Sci., (July–September 2012) 82(3):365–373.(Impact factor 0.96) https://doi.org/10.1007/s40011-012-0019-z.

2013

1. Singh A.K., Misra K*., “Human papilloma virus 16 E6 protein as a target for curcuminoids, curcumin conjugates and congeners for chemoprevention of oral and cervical cancers”, International journal “Interdisciplinary Sciences: Computational Life Sciences”. 2013, 5(2)112-118. (Impact factor: 3.492). https://doi.org/10.1007/s12539-013-0159-8.

2017

1. Kumar A., Singh A. K., Ouabain as a potential biofilm inhibitor against staphylococcus, aureus. 2017, Antimicrobial Resistance and Infection Control, 6(Suppl-3):52. (Impact factor: 6.454). DOI 10.1186/s13756-017-0201-4.

2018

1. Singh A.K.a Misra K.b, “2D-QSAR (Quantitative Structure Activity Relationship) Study f Probable Inhibitors for Oral and Cervical Cancers, Generation of Model for Pharmacophore Prediction”. Research & Reviews: A Journal of Drug Design & Discovery, 2018, 5(1)1-13.

2020

1. Kamboj Ma., Jain Kb., Singh D.Pc., Singh A.K.d Chaturvedi De.,* Molecular modeling, in-silico docking and antibacterial studies of novel template wangled macrocyclic complexes involving isatin moiety. Journal of Molecular Structure, Elsevier, 2020(1207)127602 (Impact Factor 3.841). https://doi.org/10.1016/j.molstruc.2019.127602.
2. Rani, S., Singh, A.K., Paswan, R.R. et al. Preparation, Characterization and Antibacterial Evaluation of Soy Protein Isolate Biopolymeric Films Loaded with Nalidixic Acid. J Polym Environ (2020). [Impact Factor 4.705]. https://doi.org/10.1007/s10924-020-01729-4
1. Tiwari S.K., Singh A.K., Singh A, In-silico primer designing and PCR for detection of novel coronavirus-19, Journal of Infection and Public Health, (2020) 13(12),1885-1886, ISSN 1876-0341, ( Impact factor : 7.537) doi: 10.1016/j.jiph.2020.10.010.
1. Singh S., Singh A.K. Mutated USP9X-Associated TRIM33 Inhibition in the Metastasis of Gingivobuccal Oral Squamous Cell Carcinoma EJMO. (2020); 4(4): 309-318. DOI: 10.14744/ejmo.2020.70327.

2022

1. Agnik Haldar, Singh AK*. Theassociation of long non-coding RNA in the prognosis of oral squamous cell carcinoma (2022). Gene and Genomics, volume44, pages 327–342 (Impact factor: 2.164). DOI: 10.1007/s13258-021-01194-w.
1. Singh S.  Singh A.K*., Porphyromonas gingivalis in oral squamous cell carcinoma: A review. (2022). Microbes and Infection. 24(3):104925 (Impact factor:  57) DOI: 10.1016/j.micinf.2021.104925.
1. Haldar A, Yadav K.K., Singh S., Yadav P.K., Singh A.K* In silico analysis highlighting the prevalence of BCL2L1 gene and its correlation to miRNA in human coronavirus (HCoV) genetic makeup.(2022). Infection, Genetics and Evolution. (Impact factor: 4.3) 99, 105260.DOI:https://doi.org/10.1016/j.meegid.2022.105260.
2. Yadav P.K., Singh A.K*, A Review of Iron Overload in Beta-Thalassemia Major, and a Discussion on Alternative Potent Iron Chelation Targets. (2022). Plasmatology, Volume 16: 1–9. DOI: 10.1177/26348535221103560. 
1. Yadav K. K, Anil Kumar A, Singh A.K*.A systems biology approach towards oral cancer using computational tools and techniques. Chemometrics and Intelligent Laboratory Systems 231 (2022) 104709.(2022) Impact Factor ( 4.175) org/10.1016/j.chemolab.2022.104709.
1. Yadav K.K., Singh A.K.* Topology based Protein-protein interaction analysis of Oral cancer proteins. Current Science. (2022) CURRENT SCIENCE, 123, NO. 10, 25 NOVEMBER 2022. 1216-1224. (Impact Factor: 1.169). Doi: 10.18520/cs/v123/i10/1216-1224.

2023

1. Barik K.1 Praffulla A K.1, Singh A.K.1, Kumar A1., Potential therapeutic targets for combating Mycoplasma genitalium, 3 Biotech (2023) 13: 9. Impact Factor (2.893). https://doi.org/10.1007/s13205-022-03423-9.
1. Singh S., Yadav P.K., Singh A.K.*, In‐silico structural characterization and phylogenetic analysis of Nucleoside diphosphate kinase: A novel antiapoptotic protein of Porphyromonas gingivalis. J Cell Biochem. 2023;1–12,Impact Factor (4.48). DOI: 10.1002/jcb.30389.

2012

1. Singh A.K1. Bhargava A1., Gaur R2., “Role of Bioinformatics in Microbial study “by in book titled “Microbial Application” (Eds. Gaur R., Malhotra S. and Pandey R.R.) K. International Publication, New Delhi. 2012. ISBN: 9789381141014
2. Bhargava A1., Singh A.K1., Gupta V.K. and Gaur R., “Microbes for Heavy Metal Remediation”, in book titled Biotechnology of Microbial Enzymes (Eds. Gaur R., Malhotra S. and Pandey R.R.) I.K. International Publication, New Delhi. ISBN: 9789381141014
3. Singh A.K. Gupta V.K.,. “Biological Databases for Microbial Pathways and Enzymes for pathogenesis” in Book tilted Biotechnology of Microbial Enzymes (Eds. Vijai Kumar Gupta and Manimaran Ayyachamy (National University of Ireland, Galway, Ireland), 2012 International Publ, New Delhi. ISBN: 978-1-62100-197-3.
4. Singh A.K., Bhargava A., Kaur G., Sharma A., Misra K., Bioinformatics tools and resources for cancer diagnosis and drug development. In book titled “Horizons in cancer research” 2012, vol 51 Publishers Nova International USA.

2015

1. Singh A.K., Misra K. "Next Generation Sequencing developments in cancer research by Bioinformatics approaches in book Horizons in cancer research”, Publishers Nova International USA. 2015, ISBN: 978-1-63482-627-3.

2017

1. Singh A.K. “Advances in Computer Aided drug designing” in book “Biotechnology Recent trends and emerging dimension”, Ed. Atul Bhargava and S. Srivastava Publisher Taylor and Francis , 2017CRC press. ISBN: 9781138561083.

2020

1. Halder A.a, Yadav K.b , Katara P. C, Singh A.K. * “Bioinformatics resources for the prediction of cancer prognosis and its recurrence, in book “Recent Trends in computational Omics Concept and Methodology, Ed. Pramod Katara, 2020. Nova Science Publisher, USA.

2021

1. Haldar A.a, Singh A.K.* “Next-Generation Sequence Analysis for Clinical Applications, in Book Titled “1st Edition Translational Bioinformatics Applications in Healthcare Edited By Khalid Raza, Nilanjan Dey. 2021. ISBN 9780367705701, 23-40. CRC press. Taylor and Francis group.

    

• Projects :

1. Member of Bioinformatics Society of India.
2. Life Member  of  UPASTA  (Uttar  Pradesh  Association  for  science  and  Technology Advancement)
3. Life Member of IACSIT [International Association of Computer Science and Information Technology], Singapore, December 2012.
4. Member of International association of Engineers, Hong Kong, Since October 2014.
5. Life Member of World Academy of Science, Engineering and Technology
6. Member (2018-19) Institute Innovation Council under MHRD.
7. Life Membership of Bioinformatics and Drug Discovery Society (BIDDS) (Membership number - BIDDS17-290) (Date of Membership: 09/02/2021)
8. Senior Member of Hong Kong Chemical, Biological & Environment Engineering Society (HKCBEES). (Date of Membership:07/02/2023)